Journal: Journal of Clinical Medicine
Article Title: Pulsed Field Ablation: A Comprehensive Update
doi: 10.3390/jcm13175191
Figure Lengend Snippet: Summary of pre-clinical studies on ventricular PFA.
Article Snippet: Kawamura et al. [ ] , 2023 , Healthy swine. , Lattice tip ablation catheter (Sphere-9, Affera). 7.5 Fr bidirectionally deflectable shaft with a lattice tip containing 9 mini-electrodes. , Monopolar biphasic waveform (2000 V, 4-s duration deliveries). , Endocardial PFA and RFA , At 1-h post-PFA, myocytes were disrupted. Swollen mitochondria with degenerating nuclei and condensed chromatic were seen. At 4 h post-PFA, there was worsening edema. Histologic features of PFA included sparing of vessels and sharp lesion margins..
Techniques: Electroporation, Ex Vivo, Modification, Isolation, Biomarker Discovery, Muscles, Serial Time-encoded Amplified Microscopy